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Personalised Medicine: How Pharmacogenomics (PGx) can Transform Patient Care | BPS Live
This BPS Live webinar explores the field of Pharmacogenomics (PGx) and its significant impact on personalised medicine. PGx is the study of how genes affect a person's response to drugs. This emerging field combines pharmacology and genomics to develop effective, safe medications and doses tailored to a person's genetic makeup.
Agenda:
00:00:00: 'Introduction to pharmacogenomics & benefits'
Dr Mark Hudson-Peacock - Chairman & Medical Director, Mantara
00:12:18: 'Technical considerations and future trends of PGx'
Professor Daniela Steinberger - Scientific Cooperation Partner, Mantara
00:34:10: 'Clinical examples & considerations'
Dr Nathan Hudson-Peacock - Non-Executive Director, Mantara
00:58:58: 'Summary & conclusion'
Dr Mark Hudson-Peacock - Chairman & Medical Director, Mantara
01:04:09: 'Open panel discussion with all speakers'
Dr Mark Hudson-Peacock - Chairman & Medical Director, Mantara
Professor Daniela Steinberger - Scientific Cooperation Partner, Mantara
Dr Nathan Hudson-Peacock - Non-Executive Director, Mantara
01:26:26: 'Closing remarks'
Dr Nathan Hudson-Peacock - Non-Executive Director, Mantara
---
🧬 Join the UK Pharmacogenetics & Stratified Medicines Network for free: www.uk-pgx-stratmed.co.uk/
💜 Read the 'Personalised Prescribing' report publish by the British Pharmacological Society and the Royal Society of Physicians: www.bps.ac.uk/personalised-prescribing
🏥 NHS Genomic Medicine Service: www.england.nhs.uk/genomics/nhs-genomic-med-service/
⚕️ Pharmacogenomic and medicines optimisation NHS genomic network of excellence: www.england.nhs.uk/genomics/nhs-genomic-networks-of-excellence/#pharmacogenomics
📆 BPS events calendar: www.bps.ac.uk/events
✨ Become a BPS member: www.bps.ac.uk/membership-awards/society-membership
---
🎙️ BPS Live is a series of free webinars run by the British Pharmacological Society. They cover a variety of topics across the field of pharmacology. Find out about future webinars and events: www.bps.ac.uk/events
---
Key Topics Covered:
- Introduction to Pharmacogenomics:
- Definition and scope of Pharmacogenomics.
- Discussion of panel testing vs single testing
- Mechanisms of PGx:
- How genetic variations influence drug metabolism and efficacy.
- The role of genetic testing in identifying these variations.
- Clinical Applications:
- Case studies showcasing successful integration of PGx in patient care.
- Examples of drugs with well-established pharmacogenomic guidelines.
- Benefits of PGx in Personalised Medicine:
- Improved drug efficacy and safety.
- Reduction in adverse drug reactions and trial-and-error prescribing.
- Considerations:
- Ethical, legal, and social implications.
- Cost, accessibility, and the need for healthcare provider education.
- Future Directions:
- Research trends and potential future developments in PGx.
Learning Outcomes:
- Understanding of Pharmacogenomics:
- Gain a comprehensive understanding of what pharmacogenomics is and how it operates -within the broader scope of personalised medicine.
- Knowledge of Genetic Influences on Drug Response:
- Learn how genetic variations can affect drug metabolism and response, leading to more effective and safer medication use.
- Application in Clinical Practice:
- Recognise the practical applications of PGx in clinical settings through real-world examples and case studies.
- Identification of Benefits and Challenges:
- Understand the benefits of PGx in improving patient care and the challenges that need to be addressed for its broader implementation.
- Awareness of Future Trends:
- Stay informed about the latest research and future directions in the field of Pharmacogenomics, and how it might shape the future of personalised medicine.
By the end of the webinar, participants will be equipped with the knowledge to understand the transformative potential of PGx in patient care and will be aware of both the opportunities in implementing PGx in clinical practice.
Переглядів: 119

Відео

Career Opportunities in Pharmacology and Drug Discovery | BPS Live
Переглядів 3528 днів тому
In celebration of a decade of progress for PR&P, this BPS Live Webinar explores the wide range of research and career opportunities within the field of pharmacology and drug discovery. A diverse panel of presenters discuss their journeys that have crossed the boundaries of academia and industry (occasionally several times!). They discuss the many and varied opportunities for career development ...
New Insights in Pharmacology: Highlights from the BJP and BJCP
Переглядів 4728 днів тому
Welcome and Introduction: Professor Serge Cremers & Professor Péter Ferdinandy Talk 1: "Defining and unpacking the core concepts of pharmacology: a global initiative” Professor Clare Guilding, Newcastle University, UK Talk 2: "Phase 1 study of KCL-286, a nuclear receptor drug for nerve regeneration” Professor Jonathan Corcoran, Kings College London Talk 3: “Exploring the Role of ChatGPT in Phar...
Creating engaging content: How to bring science to life for a public audience
Переглядів 41Місяць тому
How can you translate your science into exciting content that will engage the audience you want to reach? This Engagement Webinar features three talks that look at different types or content and platforms you can use to share you science with different audiences. Agenda: 00:00 'Introduction' Harriet Kotta - Head of Marketing & Communications, British Pharmacological Society 00:26 'Designing a p...
Psilocybin - could "magic mushrooms" be the key to treating depression and other mental illness?
Переглядів 1 тис.2 місяці тому
Professor David Nutt explains how psilocybin - a compound found in some mushrooms - could be used by doctors to help patients with treatment-resistant depression. He explains how psilocybin works in the brain, and how more research is needed to see if it could help some people living with mental health conditions. Further reading on psilocybin and other psychedelics: Daniel Hoyer (2023). 'Psych...
Community guidelines for GPCR ligand bias: IUPHAR review 32 - interview with Prof David Gloriam
Переглядів 1858 місяців тому
Read the Community guidelines for GPCR ligand bias: IUPHAR review 32: bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15811 Browse the British Journal of Pharmacology (BJP): bpspubs.onlinelibrary.wiley.com/journal/14765381 Submit your papers to BJP: mc.manuscriptcentral.com/bjp BJP Editor Dr Shivani Sachdev interviews Professor David Gloriam about the Community guidelines for GPCR ligand bias: ...
How to communicate about animal research - John Meredith from Understanding Animal Research
Переглядів 73Рік тому
Communicating about the use of research animals is an essential skill for many scientists, particularly preclinical researchers. In this BPS Engagement Webinar, John Meredith (Education and Outreach Manager for Understanding Animal Research) shares advice on how to effectively discuss the ethical and scientific aspects of animal research. This video will give you the skills to engage others, fr...
What is Public Engagement? - Paul Manners, Associate Professor in Public Engagement at UWE Bristol
Переглядів 57Рік тому
Paul Manners is Co-director of the National Co-ordinating Centre for Public Engagement (NCCPE) and Associate Professor of Public Engagement at UWE, Bristol. In this webinar recording, he explains the reciprocal benefit of engaging the public in pharmacological research. If you have any questions about this webinar, please get in contact via getinvolved@bps.ac.uk 📆 BPS events calendar: www.bps.a...
Drug Targets in Cardiovascular Disease - Full live stream recording
Переглядів 450Рік тому
'Drug Targets in Cardiovascular Disease: Developing a portal into the guide to Pharmacology for Cardiovascular clinical and basic researchers' was a one-day webinar hosted by the British Pharmacological Society and The British Heart Foundation on 18 April 2023. Building on the work of the IUPHAR/BPS Guide to Pharmacology Database, the webinar brought together established leaders in the cardiova...
Professor David Nutt - Psychedelic drugs as potential treatments for mental health conditions
Переглядів 3,8 тис.Рік тому
Psychedelic drugs, also known as hallucinogens, act on the brain to cause changes in perception, mood and cognitive functions. Professor David Nutt talks about research into how psychedelic drugs, like psilocybin (magic mushrooms) LSD and DMT (ayahuasca), are working in the brain. David also discusses the potential of psychedelic drugs as new treatments for mental health disorders such as depre...
Dr Nilima Kshirsagar speaks to Dr Joshua Dignam & Dr Aisah Aubdool about her involvement at WCP2023
Переглядів 139Рік тому
Dr Nilima Kshirsagar speaks to Dr Joshua Dignam and Dr Aisah Aubdool about the 'Prescribing skills training and assessment: Global perspectives, future plan' session at WCP2023 - 6 July 2023, 4.05pm - 6.30pm View the WCP2023 programme: www.wcp2023.org/programme Dr Nilima Kshirsagar is Founder President of the South Asian chapter of the American College of Clinical Pharmacology; and a member of ...
Highlights from the World Congress of Basic and Clinical Pharmacology 2023
Переглядів 502Рік тому
In July 2023, the British Pharmacological Society and IUPHAR hosted the 19th World Congress of Basic and Clinical Pharmacology (WCP2023). Over 2,000 delegates joined us in Glasgow, Scotland for a week of science, networking and social events. wcp2023.org/ British Pharmacological Society: www.bps.ac.uk/ Join us for our annual meeting, Pharmacology 2024: my.bps.ac.uk/events/details/?id=3f7e8841-1...
Prof Amrita Ahluwalia, Secretary-General of WCP2023, talks to Dr Joshua Dignam and Dr Aisah Aubdool
Переглядів 167Рік тому
Professor Amrita Ahluwalia, Secretary-General of WCP2023, talks to Dr Joshua Dignam and Dr Aisah Aubdool about the sessions she is most looking forward to at WCP2023, as well as her advice for Early Career Researchers. www.wp2023.org 'The importance of interrogating sex differences in cardiovascular physiology and disease' | 4 July 2023, 9:45 am - 12:10 pm: wcp2023.org/events/the-importance-of-...
Prof Helen Kwanashie talks to Dr Joshua Dignam & Dr Aisah Aubdool about her excitement for WCP2023
Переглядів 158Рік тому
Register now: www.wcp2023.org/register View the WCP2023 programme: www.wcp2023.org/programme View activities and resources for Early Career Researchers (ECRs): wcp2023.org/early-career-researchers-resources/ Professor Helen Kwanashie talks to Dr Joshua Dignam and Dr Aisah Aubdool about the debates and satellite meetings she will be speaking at during 19th World Congress of Basic and Clinical Ph...
Professor Masashi Yanagisawa talks to Dr Joshua Dignam & Dr Aisah Aubdool about his WCP2023 keynote
Переглядів 788Рік тому
Register now: www.wcp2023.org/register View the WCP2023 programme: www.wcp2023.org/programme View activities and resources for Early Career Researchers (ECRs): www.wcp2023.org/early-career-... Professor Masashi Yanagisawa talks to Dr Joshua Dignam and Dr Aisah Aubdool about his keynote lecture at the 19th World Congress of Basic and Clinical Pharmacology (WCP2023), titled 'Toward the mysteries ...
Professor Garret A. FitzGerald talks to Dr Aisah Aubdool about his WCP2023 Opening Keynote Lecture
Переглядів 237Рік тому
Professor Garret A. FitzGerald talks to Dr Aisah Aubdool about his WCP2023 Opening Keynote Lecture
Choosing the right experimental design
Переглядів 284Рік тому
Choosing the right experimental design
Professor Sarah Tabrizi talks to Dr Aisah Aubdool about her keynote session at WCP2023
Переглядів 263Рік тому
Professor Sarah Tabrizi talks to Dr Aisah Aubdool about her keynote session at WCP2023
Professor Sir Mark Caulfield talks to Dr Aisah Aubdool about his keynote lecture at WCP2023
Переглядів 358Рік тому
Professor Sir Mark Caulfield talks to Dr Aisah Aubdool about his keynote lecture at WCP2023
Professor Ingolf Cascorbi shares his excitement for WCP2023
Переглядів 375Рік тому
Professor Ingolf Cascorbi shares his excitement for WCP2023
Where do cancer medicines come from?
Переглядів 471Рік тому
Where do cancer medicines come from?
CFTR Modulators for Cystic Fibrosis + Closing Remarks & Prizes of Pharmacology 2022
Переглядів 364Рік тому
CFTR Modulators for Cystic Fibrosis Closing Remarks & Prizes of Pharmacology 2022
Oral Communications - Education & Skills - from Pharmacology 2022
Переглядів 96Рік тому
Oral Communications - Education & Skills - from Pharmacology 2022
From pharmacology to clinical pharmacology - Lilly Prize Lecture 2022
Переглядів 250Рік тому
From pharmacology to clinical pharmacology - Lilly Prize Lecture 2022
Centenary of Insulin
Переглядів 132Рік тому
Centenary of Insulin
Evrysdi® (risdiplam) - Drug Discovery of the Year Prize Lecture 2022
Переглядів 983Рік тому
Evrysdi® (risdiplam) - Drug Discovery of the Year Prize Lecture 2022
Oral communications - Neuropharmacology - from Pharmacology 2022
Переглядів 234Рік тому
Oral communications - Neuropharmacology - from Pharmacology 2022
Anti-emetic drugs - WDM Paton Memorial Lecture
Переглядів 75Рік тому
Anti-emetic drugs - WDM Paton Memorial Lecture
Innovations in RNA-based therapies
Переглядів 177Рік тому
Innovations in RNA-based therapies
Individual variability in drug response: looking forward
Переглядів 295Рік тому
Individual variability in drug response: looking forward

КОМЕНТАРІ

  • @UPie-pz7ez
    @UPie-pz7ez 17 днів тому

    L dopa fixed me. Alright?

  • @markpurslow7446
    @markpurslow7446 17 днів тому

    NICE doesnt have a mandate from government to determine who gets treatment does it?

  • @VinhNguyen-yp8wi
    @VinhNguyen-yp8wi 18 днів тому

    Xin tiền việt

  • @Ayrad160
    @Ayrad160 22 дні тому

    I am in love with this lady 😊

  • @queentina9020
    @queentina9020 24 дні тому

    Sir does microdising also work great?

  • @kaylagreenstien9069
    @kaylagreenstien9069 Місяць тому

    "The main areas of serotonin research provide no consistent evidence of there being an association between serotonin and depression, and no support for the hypothesis that depression is caused by lowered serotonin activity or concentrations." - Moncrieff, J., Cooper, R.E., Stockmann, T. et al. The serotonin theory of depression: a systematic umbrella review of the evidence. Mol Psychiatry 28, 3243-3256 (2023).

  • @navanmaharaj9805
    @navanmaharaj9805 Місяць тому

    Beautiful. I love how this is becoming mainstream. I'm so grateful to David Nutt.

  • @catarinasantos3018
    @catarinasantos3018 2 місяці тому

    You are incredible

  • @mmrutman
    @mmrutman 2 місяці тому

    Very on point! Thank you! ❤

  • @craspouille4
    @craspouille4 2 місяці тому

    Do a video on ketamine

  • @TJHambright-fk7eq
    @TJHambright-fk7eq 3 місяці тому

    It's the food! Too much fat causes diabetes.

    • @saidarav7583
      @saidarav7583 Місяць тому

      actually cause is carbohydrates

    • @TJHambright-fk7eq
      @TJHambright-fk7eq Місяць тому

      @@saidarav7583 no, it's fat, sugar (includes simple carbs) and meat and dairy. That's what is poisoning people and making them sick.

    • @davidiglesias9549
      @davidiglesias9549 Місяць тому

      No. Fat clogs up the cells paralyzing insulin. Carbs dont cause diabetes

  • @janettempest716
    @janettempest716 3 місяці тому

    Well done thank you 🙏 ❤

  • @dr.tanveerahmedph.d4176
    @dr.tanveerahmedph.d4176 3 місяці тому

    Understanding the costs associated with cancer is vital in order that resources are used for maximum effect. And investing in prevention and early intervention is critical if we are going to reduce the emotional and physical impact of cancer on individuals, families, friends and those that care for people with cancer. Calculating the health care and wider costs of cancer - as well as assessing the cost-effectiveness of prevention, early intervention and treatment - is a fundamental challenge faced by decision makers across the health and social care system. The costs of cancer can be felt at an individual level: work by Macmillan has shown that most (83%) cancer patients incur an average cost of £570 per month as a result of their illness. It can also be felt in the national economy: Oxford University estimate the cost of cancer to the economy is £7.6 billion a year due to premature deaths and time taken off work. Costs and the health system The Independent Cancer Taskforce Report (ICTR) set out the need for there to be clearer accountability of spend on cancer and emphasised the need for action in prevention and early diagnosis to reduce the longer term burden on the health system. It says: “The National Audit Office has estimated cancer services cost the NHS approximately £6.7bn per annum in 2012/13. The Five Year Forward View projections indicate that this will grow by about 9% a year, implying a total of £13bn by 2020/21.” Recommendation 95 in the strategy specifically asks that: “NHS England and Public Health England should work with Monitor and other bodies to consider how to develop better health economic evaluation of new service models and interventions.” We have a dedicated health economics team that commissions work to assess the economic impact of prevention and early intervention, and an example of this is recent work on bowel cancer in direct response to Taskforce Recommendation 95. This work has summarised the available cost-effectiveness evidence. Cost-effectiveness is a key concept in health economics and is concerned with the value we get from the money spent - where value is often expressed in terms of improving both survival and quality of life. For instance if we invested resources in the best possible way in bowel cancer then we would see improvements in survival, and also improvements in the quality of life of individuals who are staged earlier and therefore do not suffer the more unpleasant effects of treatment that could potentially be avoided. This is why a ‘return on investment’ (RoI) type approach has been followed in this work: how do we make sure that resources are invested in such a way that we achieve health gains at the same time as avoiding health care and other system costs further down the line.

  • @lfcmonkeyyyman6229
    @lfcmonkeyyyman6229 3 місяці тому

    Well explained, but I wish you had looked directly at the camera, rather than looking to one side of it... makes it feel like you're talking to someone to the right and behind me 😄

  • @Priyayadav83737
    @Priyayadav83737 4 місяці тому

    Kuch smj nhi aya❤

  • @methodsignature
    @methodsignature 4 місяці тому

    I thought the video was gonna be too short b.c. for detail. Then I though it was taking a long time to get to the actual mechanics so was going to be even less time. Then she gave a perfectly coherent and understandable explanation of how penicillin works. Then she gave bonus material. Fantastic work!

  • @Rick_Cleland
    @Rick_Cleland 5 місяців тому

    Paracetamol doesn't work, it does nothing!! *_NOTHING!!_*

  • @gaylegaming1063
    @gaylegaming1063 5 місяців тому

    DEAR association members.. i wanna join Birthish pharmacological society

  • @gaylegaming1063
    @gaylegaming1063 5 місяців тому

    basically. iam a PHARM D graduate... mam.. tell me any suggestion after pharm D

  • @gaylegaming1063
    @gaylegaming1063 5 місяців тому

    iam from 🇮🇳 india (we are not growed up till.. if u are not come here)... thank u for occupying us for olden days.... ❤❤❤❤ i love u dear brithishers

  • @gaylegaming1063
    @gaylegaming1063 5 місяців тому

    which pg course u have been completed..? mam

  • @vdavis1959
    @vdavis1959 5 місяців тому

    easy explanation. I take metformin and have nothing but good results. weight loss, sugar levels and changed my diet. Diet is the key here, no sugar, soda's, alcohol, and you will be fine. Get a CGM and see what foods affect your sugar. I was surprised to learn what raised my sugar. Metformin and CGM. Great combination. (CGM: Continuous Glucose Monitoring).

  • @halaldunya918
    @halaldunya918 5 місяців тому

    Paracetamol causes brain damage, and ruins your body, and deteriorates your nervous system.

  • @Nelson_manuel28
    @Nelson_manuel28 5 місяців тому

    This is the nasty drug that kills Syd Barrett

    • @DrewNorthup
      @DrewNorthup 21 день тому

      Syd had a great many problems, including alcoholism, depression, anxiety, reduced lung function, and malnutrition. It is doubtful that LSD is what did him in.

  • @veronicatraviglia1586
    @veronicatraviglia1586 5 місяців тому

    Ti's video is a lot of rubbish

    • @patpending8134
      @patpending8134 5 місяців тому

      Er, okaay... But who is Ti and why are you criticising their video?

  • @fullstack5461
    @fullstack5461 5 місяців тому

    Don't have a cure for diabetes 😂. Do intermittent fasting eating once a day. No further medicine needed, and in this high inflation period, you will also save money on food. THE END

  • @angelvisions444
    @angelvisions444 6 місяців тому

    Nice eyes Dr Andrew!

  • @Alan-oj3ps
    @Alan-oj3ps 6 місяців тому

    Thx 4 the tip

  • @misterjohn007
    @misterjohn007 6 місяців тому

    Big Legend

  • @heroruiz1725
    @heroruiz1725 6 місяців тому

    I’m interested in clinical pharmacology. I am a college student and my academic counselor wants me to speak with a clinical pharmacologist to get more of what a clinical pharmacologist does. If anyone can tell me how to speak with one that would be great

  • @MariosSuper-ks5vw
    @MariosSuper-ks5vw 7 місяців тому

    Να σου σιεω

  • @swanofusk9314
    @swanofusk9314 7 місяців тому

    Yeah just tell us Fairy Tales? They wont show us the gross things the y do. Like the lab at Oxford Univ. that has the macaques wearing cute little crocheted beanies to stop them messing with the Electrodes in their skull.

  • @javierescontrias
    @javierescontrias 7 місяців тому

    Ok. But why dies metmorphin make me extremely tired after taking it? I asked my Dr and she responded with "huh?" And nothing else.

    • @punitgoyal2236
      @punitgoyal2236 Місяць тому

      Check ur phosphorus level to see if low. My 23yr old daughter literally died cause of it. Pl check for low phosphorus level.

  • @sumit850
    @sumit850 8 місяців тому

    Thanks for the info. Love the accent.

  • @CatSullivanpallcare
    @CatSullivanpallcare 8 місяців тому

    Hello there. I’m trying to get hold of Fran. Does anyone know the best way to do it? Is she still at UCH. We used to work together and I’m doing relevant work, so it would be good to catch up

  • @astrogamesjejeuehehe
    @astrogamesjejeuehehe 8 місяців тому

    I'm nothing like y'all 😎😭😭😭

    • @Gatito109
      @Gatito109 8 місяців тому

      Eating a burger with no honey musturd😎😎😡😡

    • @Rick_Cleland
      @Rick_Cleland 5 місяців тому

      ♫ ♪ *_'Cause I'm not like everybody else!!_* ♫ ♪

  • @nourahmed2318
    @nourahmed2318 8 місяців тому

    Lap lap lap just taking for meny We are needing mony only No more

  • @mohamedbah3943
    @mohamedbah3943 8 місяців тому

    Help prioritise the healthcare needs and guide your decision

  • @VultureSunset
    @VultureSunset 9 місяців тому

    Most useless "pain killers" ever absolutely useless.

  • @eseoghenetv
    @eseoghenetv 9 місяців тому

    This woman prof helen is my menthor.❤

  • @pallabsarkar1787
    @pallabsarkar1787 9 місяців тому

    Wonder ful discus.

  • @williamclark6352
    @williamclark6352 10 місяців тому

    She said Diabetes is a life long disease!!!! LMAO. Type 2 is not

    • @Carelmartyn
      @Carelmartyn 8 місяців тому

      It is.

    • @patpending8134
      @patpending8134 5 місяців тому

      LMAO sums up you intellectual level. Does you Mom know you're using her computer to play on the internet?

    • @mroosie7488
      @mroosie7488 Місяць тому

      @@Carelmartynyou can reverse type 2

  • @DoralbaRojas
    @DoralbaRojas 10 місяців тому

    BEN JIJ ALS BONNIE & CLYDE OF BEN JE DAAR IN VERSTRIKT GERAAKT IK STA TEGEN NIEMAND TE LIEGEN,IK PROBEER HIER EEN VADER EN MOEDER EN KINDEREN DAT GING OOK VIA VOETSTAP EN AUTO, NIET TE LATEN LIQUIDEREN HIER ZIT IETS TE TOEVALLIG OOK NAAR VAN DE VALK ANDERS HEEFT DE PRESIDENT EN BOUTERSE EEN HEEL GROOT PROBLEEM,DAT KRIJG JE VAN TEVEEL EXPERIMENTEREN EIGENWIJS VIA ACTEREN SLIJMEN,MIJN PRIVÉLEVEN ONTNEMEN NAAR HEALTY MIND COMBINEREN,WHATCH WIE HIER OP RELIGIES STAAN TE MISHANDELEN SCHIJNHEILIG STIEKEN EN WEERSVOORSPELLINGEN KAN IK VIA ACTEREN SLIJMEN NAAR PARAPSYCHOLOGIE PARAPSYCHOLOGIE CHIRURGIE,IN THE JUNGLE THEY PRAY CLEVER ,KAN OVERSLAAN NAAR JALOUSY,DAT IS WAT DIE NARCIST NOG INZICHZELF INZIET NAAR ONTKENNINGSFACE OVER ZAKELIJKE NARCISME EN PSYCHOPATHISCHE NARCISME DICHT BIJ JEZELF OVER ZICHZELF TEGEN ZICHZELF ZICH ZELF EERLIJK AANSPREKEN NIET TEGEN ZICHZELF LIEGEN OOK ALS JE MET FAM RELIGIE HOUDT COMUNICATIESTOORNISSEN KRIJG JE HIER VAN EINSTEIN WERD 47JAAR 150 YEAR MINIMAL WERK IK LIEVER NAARTOE OOK NAAR MIJN PRIVÉLEVEN,WAT EIGENAARDIGE VRIENDSCHAPPELIJK DAT GESTALK PROBLEEM BELASTINGDIENSTONTDUIKINGEN OP FACEBOOK TWITTER ENZ HEB JE MIJ OF WERK JE VIA DRAMA, MENSTRUATIECYCLUS GECONDOLEERD MET DE HUMEUR VAN GISTEREN NAAR DE OVERGANG,MENSTRUATIECYCLUS UITSTELLEN, FATSOEN BEHANDELEN IEMAND MAKT DEZE VROUW MEISJE RIDICICOULOUS.

  • @DoralbaRojas
    @DoralbaRojas 10 місяців тому

    KIJK JE UIT VIA ROEMENIË ONTNEEMT DIE JE NU,HOE DENK JE OVER PEDOFIELE VERSLAVING,OPIUM EN LSD,STOFDEELTJES,WAT IS DIT VOOR RARE HIPPIE TIMEMINGEN RIDICICOULOUS,IK WORDT VAN DIT SOORT BEZETENHEID PLAAG AFSTANDELIJKER,DIT IS WAAROM IK STEEDS BOZER MOET WORDEN MIJN KINDEREN BANG MAKEN,KICKEN ZE DAAR OP ANDEREN IN PANIEK LIEGEN ?,WAT TOEVALLIG ZEG JA JA GORDELROOS KRIJG JE DAT VAN EET OF NAAR AIDSVACAIN VOOR LATEN GAAN OP LEUKEMIE KANKER PROSTAATKANKER,WEET JIJ HOELANG IETS VAN KANKER NIET OPGELOST IS,VREEMDE WETENSCHAPPERS,LOONBELASTING, SPOTTEN MET ETEN EN DRINKEN HYGIËNE EN SPOTTEN MET ZIEKTES OPROEPEN WAT JE ZELF NOOIT HEBT GEHAD NAAR IK BEN DE KONINGIN VAN COLOMBIAANSE BESCHERMING PERSOONSGEGEVENS EN VOOR INSPECTIE EN CBR REGELS BLOWEN EN DRANK IN DE AUTO EN WELKE KANT VAN DE WEG HOOR JE NIET TE CREËREN DIGITALE DEMENTIE

  • @jankoro221
    @jankoro221 11 місяців тому

    I am being treated for this medication. I want to know why when I drink this medication I cannot ejaculate. Is there a treatment for this problem?

  • @sinmiloluwaoriade1452
    @sinmiloluwaoriade1452 11 місяців тому

    I want to become a clinical pharmacologist I'm a postgraduate student studying pharmacology as a degree in Nigeria here How do I go about it BSP?

  • @TehLiquid
    @TehLiquid 11 місяців тому

    Mysterious?! How can you make and sell a product that is quoted as mysterious, wtf

  • @nl2766
    @nl2766 11 місяців тому

    We are in deceptive times, for sure.

  • @alfiecdyson
    @alfiecdyson 11 місяців тому

    Where in Scotland is he next talking?

  • @melissakeith1084
    @melissakeith1084 11 місяців тому

    Promo-SM 😈

    • @jimstirling7223
      @jimstirling7223 7 місяців тому

      Would you expect an academic to promote someone else ? There are no shortage of egotistical clickbait channels on YT where your comment would be more relevant